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Is India prepared for Covid-19 Vaccination? Storage, Transportation and Mock Drills

The new year started with a glorious update. DGCA has approved restricted emergency use of Oxford-AstraZeneca and Bharat Biotech shots. Both the vaccines will soon hit the market. The first in line to receive the vaccines is our health workers who have been working tirelessly since last one year. Other people who come under the priority list are those above 50 years of age and those below it having comorbidities.

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The main concern in 2020 was till when we can expect a vaccine? Now, in 2021, our concern is how the developed vaccine will be distributed? When it comes to India, the concern grows even further. How can the government vaccinate a country of more 1.3 billion people? Is it necessary to vaccinate everyone? How long will it take to manufacture enough vaccines for the population? How will this fragile vaccine be distributed? This all sums up to one question: How prepared India is for the Covid-19 vaccination process? Let’s find out some of the recent developments as we step in the new phase of the war against Coronavirus. 

The cold storage & training issues

The vaccines approved needs a minimum temperature every time to be effective. This temperature may vary from 2 degrees to 8 degrees. Thus, the Indian government had to put special attention to cold storage and transportation. Last month, the government notified that 29000 cold chain points, 240 walk-in coolers, 70 walk-in freezers, 45000 ice-lined refrigerators, 41000 deep freezers and 300 solar refrigerators will be utilized in the vaccination process. Many of these units have already been transferred to the states so that the vaccination drive does not get delayed. Glass vials and syringes need to be stocked in huge numbers.

Godrej is one of the leading private companies which is looking to build products which can help the government in this vaccination process. They have already announced that it will commission 11,856 units of vaccine refrigerators and deep freezers within the next 6 months. This comes after they won a tender under the Universal Immunization Programme of the union health ministry. 

Our airports have to play a pivotal role in the speedy transportation of vaccines. India’s largest airport which is in Delhi has already geared itself with cold storage facilities since last month. It has developed cold chambers which can store at least 27 lakh vials at a given point. Also, they have the capability to transport 80 lakh vials per day. This is great news for the people of Delhi who have already seen three peaks of virus till now.

It is clear that logistics is a problem, but so is the human resource. Special training modules have been designed for every rank of personnel. Medical officers, vaccinator officers, data managers, ASHA coordinators, people in transport & storage, all are being trained to deal with this special and limited vaccine. More than 1,14,000 vaccinators have already been trained so far for the world’s largest immunisation exercise.

Mock Drill 

Any nation-wide vaccination programme imposes a huge challenge in front of the government. Any lapse during the distribution can lead to fatal consequences. A more cautious approach is required and this is what the Indian government has put their focus on. 

Recently, they have conducted mock vaccine drills in four states of the country to test the smoothness of the operations. These four states were Andhra Pradesh, Gujarat, Punjab and Assam. Now, the national government has announced a dry run of vaccination will be rolled out in each state. The mock drill took place at 286 session sites across 125 districts.

This process will help the government to take note of the glitches in the system if any. The focus is to keep a check on the functionality of Co-WIN application, cold storage & transportation, and the human resource preparation which will be required when the vaccine actually comes out. 

During these dry runs, dummy vaccines are being transported from the central storage facility to cold chain points. Volunteers were sent SMSes with a date, place and time to get vaccinated. Every person who is vaccinated will be monitored for the next 30 minutes to see if there’s any ill-reaction happening to the individual. The whole process gives a rough idea about the time required and logistics that will be involved every day.

Conclusion

The world’s largest immunisation exercise won’t be easy at all. More than 75 lakh beneficiaries have already been registered on Co-WIN software. This number will only increase from here. The CM of Uttar Pradesh, Yogi Adityanath, has already stated that he expects vaccination to start around mid-January. Does it mean that within a fortnight, we will be seeing our health workers getting vaccinated? How successfully can India achieve this challenge? Can Narendra Modi and his government live up to the strong image it has worldwide? All of these questions will be answered in the next few weeks. Here, we hope that this immunisation drive works out well and we return to the pre-covid life as soon as possible.

Studies actually suggest it would be well over 2022 June before we can vaccinate all of India. The vaccines are said to be safe by experts, and the vaccination process is starting very soon. What are your opinions on this largest vaccination process in the world? Let us know in the comment section!

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Stocks to Benefit from Potential Covid-19 Vaccines

The Covid-19 pandemic has caused a deep impact on people’s livelihoods and health. The economic and social disruption caused by this unprecedented pandemic is devastating. As of November 24, official data from John Hopkins University shows that there are more than 59 million confirmed cases of Covid-19 worldwide.

The only factor which keeps our spirits high is the fact that potential Covid-19 vaccine candidates are showing great results in the final stages of trials. Let us take a look at the updates of 4 major vaccines that could be supplied in India, as soon as they receive regulatory approvals.

  1. Oxford-AstraZeneca Vaccine
  2. Pfizer-BioNTech
  3. Gamaleya Institute-RDIF
  4. Bharat Biotech-ICMR
  5. Which Stocks Could Benefit from Vaccine?

Oxford-AstraZeneca

The AZD1222 Covid-19 vaccine is jointly developed by a Swedish-British pharma company AstraZeneca and the University of Oxford. According to trials conducted by the developers, the vaccine has shown an overall efficacy rate of 70%. An analysis issued by Oxford-AZ on 23rd November showed some very exciting results. The participants who received a lower amount of the vaccine in the first dose and then the full amount in the second dose were found to be 90% less likely to develop Covid.

The vaccine has also shown that it works across all age groups, and is also able to reduce asymptomatic infection. Another important feature of the Oxford-AZ vaccine is that it can be stored at normal fridge temperatures. This means that it would be cheaper to distribute and administer the vaccine to people. Experts believe that these 3 factors make this candidate a better choice, as compared to the results published by Pfizer and Moderna. There were no severe cases or hospitalisation in the 23,000 people who got the shot. 

The developers of the vaccine expect to supply 2.9 billion doses once they receive emergency use authorization. They have also stated that the vaccine would be made available in the UK first. The United States, the United Kingdom, and India are the main countries that have committed to buy a majority of its doses. The price of the shot has been set at $4-5.

It is expected to be cheaper in India, as the doses are also being manufactured by the Serum Institute of India (SII). The SII had partnered with AstraZeneca to develop the vaccine under the ‘Covidshield’ brand in our country There is a high chance that this vaccine will be the first to be administered to Indian citizens.

“The Serum Institute of India (SII) can apply for emergency use authorization (EUA) of the AstraZeneca and Oxford University’s COVID-19 vaccine in India once it is approved in the UK, since it is a partner developer” – Dr. Randeep Guleria, Director of AIIMS.

Pfizer-BioNTech

The Covid-19 vaccine candidate termed mRNA-BNT162 is being developed by US-based Pfizer Inc and Germany-based BioNTech. According to the final trials conducted by both companies, the vaccine has proven to be 95% effective in preventing Covid-19. Pfizer has approached the United States Food and Drug Administration (USFDA) to appeal for an emergency use authorization of its vaccine. However, a report on November 23 states that the USFDA will only assess the appeal on December 10.

Pfizer and BioNTech expect to supply 1.3 billion doses of the vaccine, as soon as they receive the approval from the USFDA. The United States, the UK, European Union, and Japan have already committed to buying the doses. The price per shot has been set at $20. Pfizer expects the vaccine to be rolled out by Christmas time in the United States.

On November 24, India’s Union Health Minister Harsh Vardhan said that India may not require the Pfizer-BioNTech vaccine. He stated that other vaccine candidates such as the one developed by Oxford-AZ are showing promising results. Also, the storage and distribution of Pfizer’s vaccine require an ultra-cold chain of minus 70 degrees. This would make it very expensive in India. However, based on India’s current Covid-19 situation, the government may consider buying a significant quantity of this vaccine.

Gamaleya Institute-RDIF

The Sputnik-V vaccine is being developed by Russia’s Gamaleya Research Centre and the Russian Direct Investment Fund (RDIF). They have partnered with Hyderabad-based Dr. Reddy’s to distribute the vaccine in India. According to the second interim analysis of 18,000 people who got the shot, the vaccine had an efficacy rate of 95%. They are currently undergoing Phase-3 trials with a total of 40,000 volunteers. RDIF has stated that Sputnik-V provides a stronger and longer-term immune response.

The developers of the vaccine expect to supply 1 billion doses of the vaccine, once they receive regulatory approvals. Russia, India, Vietnam, and Brazil have committed to buying the vaccine doses. The vaccine has been priced at $10 per shot.

Bharat Biotech-ICMR

Hyderabad-based Bharat Biotech has partnered with the Indian Council of Medical Research (ICMR) to develop India’s first indigenous Covid-19 vaccine- COVAXIN. The vaccine had initiated Phase-3 trials earlier this month with 26,000 volunteers from across 22 sites in India. This is the largest clinical trial conducted for a coronavirus vaccine candidate in India. On 22nd November, they announced that Covaxin will be at least 60% effective based on earlier trial results.

However, the company has not released the results of its Phase 1 & 2 results to the public. This makes us wonder about the actual effectiveness of the vaccine. The company expects the vaccine to be rolled out by mid-2021, after necessary approvals.

Which Stocks Could Benefit from Vaccine?

We can see that many sectors would benefit from the development of a vaccine in India. Whether it be manufacturing, storage, distribution, or administration of the vaccine, the support of many companies is needed. Earlier this month, it was announced that Pfizer’s vaccine needed a cold-storage facility to be stored and transported. On the same day, Snowman Logistics Ltd. said that they would create the necessary technology to provide logistical support for the vaccine.

Apollo Hospitals has also announced that they have the cold storage chain ready for Pfizer’s Covid-19 vaccine. They are ready to administer 10 lakh doses of the Covid-19 vaccine per day, once it is launched. The company has trained around 10,000 people to administer the vaccine in India.

Way back in July, Piramal Glass announced that they will be ready to supply more glass vials for the Covid-19 vaccines in India. They have taken proactive measures to meet any surge in demand for glass vials from the pharmaceutical industry across the globe. It has been estimated that India will require 6 crore vials for Covid-19 shots in the first six months of the vaccine being launched.

Dr. Reddy’s Laboratories will conduct all necessary trials and distribute the Sputnik-V coronavirus vaccine in India. The vaccine had arrived in Hyderabad on November 11, after regulators had approved to go ahead with the Phase-3 trial of the vaccine in India.

Just another thought that came into the team’s mind while brainstorming was that syringe manufacturers would also benefit from a vaccine. Companies like Albert David can be looked into. Also, diagnostic firms such as Dr. Lal PathLabs Ltd. would benefit from their Covid-19 testing facilities, until vaccines are launched.

What other sectors do you think will benefit from a Covid-19 vaccine?

Conclusion

As we can see, the Covid-19 vaccine candidates are showing great results. The vaccine developed by Oxford and AstraZeneca seems to be the most promising one, as compared to others. The developers of these vaccines are hopeful to supply it by the beginning of 2021. However, experts state that the distribution of the vaccine for all Indian citizens would be a major hurdle. For this, large pharmaceutical companies are also seeking logistical support from Indian firms to store and distribute vaccines. So, make sure that you follow news relating to such deals or orders.

The sentiments surrounding the efficiency of Covid-19 vaccine candidates have certainly lifted our spirits. However, do bear in mind that cases of Covid-19 are still rising, and many countries had even re-introduced lockdowns. Some parts of India are still reporting a large number of daily cases as well. Let us hope that the vaccine is available for every single citizen of India, once it is launched.